What Are GLP-1 Medications and How Do They Work for Weight Loss?

Glucagon-like peptide-1 (GLP-1) medications have emerged as a significant advancement in weight management therapies. Originally developed to treat type 2 diabetes, these medications have demonstrated notable efficacy in promoting weight loss. This article delves into the science behind GLP-1 medications, their role in regulating appetite, and examines two prominent examples: Ozempic and Mounjaro.

Understanding GLP-1 Medications

GLP-1 is a hormone naturally produced in the intestines in response to food intake. It plays a crucial role in glucose metabolism by stimulating insulin secretion and inhibiting glucagon release. Beyond its effects on blood sugar, GLP-1 influences appetite regulation by acting on the brain's satiety centers, thereby reducing food intake.

GLP-1 receptor agonists are synthetic analogs of this hormone designed to enhance its effects. By mimicking GLP-1, these medications help regulate blood sugar levels and promote weight loss through several mechanisms:

• Appetite Suppression: GLP-1 receptor agonists interact with specific brain regions responsible for appetite control, leading to reduced hunger and caloric intake.

• Delayed Gastric Emptying: These medications slow the rate at which the stomach empties its contents, prolonging feelings of fullness after meals.

• Enhanced Insulin Secretion: In response to food intake, GLP-1 receptor agonists stimulate insulin release, aiding in glucose utilization and storage.

Ozempic (Semaglutide)

Ozempic is a once-weekly injectable GLP-1 receptor agonist approved for the treatment of type 2 diabetes. Clinical studies have shown that semaglutide the generic version of Ozempic and Wegovy contributes to significant weight loss. Patients using semaglutide have reported an average weight reduction of approximately 14.9% over 26 weeks.

Mounjaro (Tirzepatide)

Mounjaro is another injectable medication that acts on GLP-1 and GIP receptors. In clinical trials, Mounjaro has demonstrated superior efficacy in weight reduction compared to other GLP-1 receptor agonists. Patients treated with Mounjaro achieved an average weight loss of up to 20.9% over 26 weeks. Our clients also experience less side effects with tirzepatide vs. semaglutide.

How are we different? We help you keep the weight off!

GLP-1 medications represent a promising avenue for weight management, offering benefits beyond traditional glucose control.  We manage our clients holistic needs, supporting nutrient depletion, and ensuring all the hormones related to maintaining your losses are in balance.   Consult with our team of professionals to determine the most appropriate solution for you, and understand the big picture about weight loss based on your individual health needs and goals.

If you have more questions about using GLP-1, we’d love to hear from you. Schedule a consultation with our team of experts at Potentia MedSpa in Lafayette, California, or call us at 510-230-2282. We are the only Functional Aesthetics Medspa in the San Francisco Bay Area, offering a combination of medical expertise, innovative technology in skin care, and holistic support for midlife hormone changes.